Chemotechnique Diagnostics AB
Information for Medical Professionals
on the
Chemotechnique e-Mag
called
"The Patch Tester"
See www.patchtester.com
The Patch Tester #1
December 2019
Contents
What's New in Patch Testing - France & Sweden propose restricting skin sensitising substances
What's New at Chemotechnique - Helping Industry Create Safe Fragrances; Following up on the European Baseline series; Gearing up Production.
Hapten of the Quarter: Isobornyl acrylate IBOA
Guest Article: Patch Testing should be a routine diagnostic procedure in children with Eczema, by Radoslaw Spiewak.
Chemotechnique Staff Interview: Bo Niklasson, Founder & CEO.
Literature Review 1: Prevalence of Contact Allergy in the general population - A systematic review and meta-analysis.
Website Review: ESCD, ILDS.
Congresses & Exhibitions.
Total Number of Pages = 18
The Patch Tester #2
March 2020
Contents
What's New in Patch Testing - NCDRG Baseline Series
Guest Article - ACD from Propolis, by Gunnar Ayman
Hapten of the Quarter - Hydroperoxides of Limonene
Literature Review 1 - ACD from Cigarette Smoking
Literature Review 2 - The final Patch Test Read
Literature Review 3 - Occupational ACD from Systemic Drugs
Literature Review 4 - IBOA fro Insulin Sensors & Sets
Literature Review 5 - Patch Test reactivity to Aluminium Chambers
Website Review - Swedish Society for Dermatology & Venerology, Nordic Dermatology Association
Congresses & Exhibitions - update
Total number of Pages = 20
The Patch Tester #3
June 2020
Contents
What's New in Patch Testing - COVID-19 Pandemic and Patch Testing
Hapten of the Quarter - MI/MCI
Hot Topic - Paediatric Patch Testing
Literature Review 1 - ACD caused by Hydroperoxides of Limonene and Dose-Response Application
Literature Review 2 - Relative Prevalence of Contact Allergens in North America in 2018
Literature Review 3 - Indium & Iridium - two rare earth metals with a high rate of contact sensitisation
Literature Review 4 - Prevalence of Contact Allergy to Metals; Nickel, Palladium & Cobalt in Southern Sweden from 1995 to 2016
Literature Review 5 - Safety Checks in Patch Testing; 5 Obstacles in the Patch Testing Obstacle Course
Literature Review 6 - Effects of Patch Testing on the course of ACD and Prognostic Factors that Influence Outcomes
Website Review - Australian College of Dermatologists, Australasian Society for Dermatology Research
Congresses & Exhibitions - update
Total number of Pages = 28
The Patch Tester #5
December 2020
Contents
What's New in Patch Testing - Comprehensive Patch Testing
What's New at Chemotechnique - Nickel Metal Barrier Cream
Hot Topics - Metal Haptens
Hapten of the Quarter - Aluminium
Literature Review 1 - Occupational Exposure to Nickel, Cobalt & Chromium
Literature Review 2 - Impact of Patch Testing on QoL
Literature Review 3 - Immune augmentation by contact
allergens to enhance the efficacy of Viral Vaccines
Literature Review 4 - Optoacoustic mesoscopy
Literature Review 5 - Freestyle Libre 2 - IBOA-free
Literature Review 6 - ACD in the Finnish Register of Occupational Diseases
Literature Review 7 - Contact Urticaria/angioedema caused by nickel from metal dental braces
Literature Review 8 - Quantification of aluminium release from Finn Chambers
Website Review - Scottish and Irish Dermatology societies
Congresses & Exhibitions - update
Total number of Pages = 40
The Patch Tester #4
September 2020
Contents
What's New in Patch Testing - North American societies update their screening series
Guest Article - Tele-Dermatology & Patch Testing
What's New at Chemotechnique - Patch Testing - an important knowledge
Topic of the Quarter - Epidemic of mask-related dermatitis
Hot Topic - Acrylates & Methacrylates in Nail Care Products
Pandemic Haptens
Literature Review 1 - Pole-Dancing Dermatitis
Literature Review 2 - Can PT with MC/MCI be optimised with a new diagnostic mix?
Literature Review 3 - Wells Syndrome following vaccination
Literature Review 4 - Food Allergens in Skin Care Products
Literature Review 5 - Oral Lichenoid Lesions - are Patch
Tests necessary?
Website Review - New Zealand dermatology websites x 3
Congresses & Exhibitions - update
Total number of Pages = 30
The Patch Tester #6
March 2021
Contents
What's New in Patch Testing - National Baseline update
Interview - David Niklasson, Business Development Director at Chemotechnique
What's New at Chemotechnique - Win a signed "Common Contact Allergens" book
Hapten of the Quarter - PEG Polyethylene Glycol
Hot Topic - Managing a Clinic in COVID-19 Pandemic
Literature Review 1 - EAACI/ARIA Position Paper on Practical Considerations on the organisation of an allergy clinic in COVID-129 Pandemic
Literature Review 2 - Anaphylaxis to the first COVID-19 Vaccine: Is PEG the culprit?
Literature Review 3 - First cases of DRESS Syndrome caused by hydroxychloroquine with a positive patch test
Literature Review 4 - Paediatric Contact Allergy: A comparative study with Adults
Literature Review 5 - Clinical significance of positive Patch Test reactions to Lanolin
Literature Review 6 - Tea Tree Oil contact sensitisation in children
Literature Review 7 - PatchTest results with the European Baseline Series and the ESSCA Network
Literature Review 8 - Developing a Cosmetic Series. Results from the ESSCA Network
Literature Review 9 - Self-reported Hand Eczema ...during the COVID-19 Pandemic
Literature Review 10 - Nickel...Sensitisation Potency and relation to Prevalence of Contact Allergy
Literature Review 11 - COVID Vaccines and safety: what the Research says
Literature Review 12 - Suitable test concentration of Cobalt and concomitant reactivity to Nickel and Chromium
Website Review - COVID-19 Clinical Guidelines; from the British Association of Dermatologists
Congresses & Exhibitions - update
Total number of Pages = 68
The Patch Tester #7
June 2021
Contents
What's New in Patch Testing - Fragrance Mixes
What's New at Chemotechnique - Book Competition Winner
Hapten of the Quarter - Fragrance Mix
Hot Topic - Hand Dermatitis
Literature Review 1 - Hand Dermatitis in the time of COVID
Literature Review 2 - ARIA/EAACI Position Paper on severe allergic reactions to COVID-19 Vaccines
Literature Review 3 - EAACI statement on the Diagnosis, Management and Prevention of severe Allergic Reactions to COVID-19 Vaccines
Literature Review 4 - ACD and Occupational Skin Diseases in Health Care Workers in Finland
Literature Review 5 - Facial Personal Protective Equipment
Website Review - BAD : Clinical Guidelines for the management of dermatology patients remotely.
American Academy of Dermatology Association : COVID-19: Guidance for dermatology patients for remote consultations
Congresses & Exhibitions - update
Total number of Pages = 44
The Patch Tester #8
September 2021
Contents
What's New in Patch Testing - Photo-assessment of Day 7 Reading of Patch Test reactions
What's New at Chemotechnique - SPIN Factor for Haptens in various Series and compared to TRUE Test
Hapten of the Quarter - Hand Sanitiser Haptens
Hot Topic - Acrylic Compounds in Occupational Dermatology
Literature Review 1 - Significance-Prevalence Index Number (SPIN)
Literature Review 2 - Methylisothiazolinone
Literature Review 3 - Improving Povidone Iodine and Iodine preparations for Patch Testing
Literature Review 4 - Contact Urticaria caused by Chlorhexidine in hydroalcoholic gel
Literature Review 5 - Contact Leukoderma following Irritant Contact Dermatitis to an isopropyl alcohol - based hand rub
Website Review - Global allergy-related organisations
Congresses & Exhibitions - update
Total number of Pages = 38
The Patch Tester #9
December 2021
Contents
What's New in Patch Testing - ACDS Core Allergen Series
What's New at Chemotechnique - Carmine Hapten
Advertorial: Nickel Barrier Cream
Hapten of the Quarter - Tea Tree Oil
Hot Topic - SARS-2 Vaccines and Cutaneous Adverse Reactions
Literature Review 1 - Patch Testing with Carmine 2.5% in petrolatum
Literature Review 2 - Patch Testing with a new composition of the Mercapto Mix
Literature Review 3 - Positive Patch Test reactions to Carba Mix and Thiuram Mix
Literature Review 4 - Epidemic on Contact Allergy to Methylisothiazolinone - The NACDG Experience
Literature Review 5 - Changes in Adhesive Ingredients in continuous Glucose Monitoring Systems
Website Review - Dermnet NZ and GlobalSkin for Patients
Congresses & Exhibitions - Update
Total number of Pages = 58
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The Patch Tester #10
March 2022
Contents
What's New at Chemotechnique - Implant Series and Division of Metal Series
Advertorial - Patch Test Chambers
Chemotechnique Staff Interview - Legal Counsel Helena Friman
Editorial - The Role of Providers of Patch Test Products
Hapten of the Quarter - Henna
Hot Topic - REACH Legislation on Tattoo Inks
Literature Review 1 - Navigating Tattoo-related Allergic Dermatitis
Literature Review 2 - Side-effects of Henna: a full review
Literature Review 3 - Impact of Nickel Oral Hyposensitisation
Literature Review 4 - Effects of TIO Nickel in Patients with ACD and SNAS
Literature Review 5 - Aluminium Contact Allergy
Literature Review 6 - Patch Testing: The Patient Experience
Website Review - Chemotechnique distributors: Australia and Caribbean
Congresses & Exhibitions - update
Total number of Pages = 32
The Patch Tester #11
June 2022
Contents
Special Feature – From the Floor at the ESCD
What's New in Patch Testing – The Use of Social Media Platforms
Chemotechnique Staff Interview - Legal Counsel Helena Friman
Editorial - The Role of Providers of Patch Test Products
Hapten of the Quarter - Aluminium
Advertorial – Nickel Barrier Cream
Hot Topic – Drug Reactions
Literature Review 1 – Skin Symptoms in Veterinary Assistant Staff and Veterinarians
Literature Review 2 – Contact Allergy to Haptens in the Swedish Baseline Series
Literature Review 3 – What is the Added Value of Patch Testing with 30 Fragrance Allergens in addition to the European Baseline Series
Literature Review 4 – The Added Value of Patch Testing Beyond the Baseline Tray
Literature Review 5 – A Comparison of Patch Testing with Nickel Sulphate in TRUE Test and in Petrolatum at 2.5% and 5% Concentrations
Literature Review 6 – European Patch Test Results with Audit Allergens as Candidates for Inclusion in the European Baseline Series
Literature Review 7 – Copper Release from Metals may Mask Positive Nickel Spot Results
Literature Review 8 – Trends in Patch Testing in the MediCare Part B Fee-for-Service Population
Website Review – AEDV-Spain + SPDV-Portugal
Congresses & Exhibitions - update
Total number of Pages = 36
The Patch Tester #12
September 2022
Contents
What's New in Patch Testing – ESCD Congress Reportage
What's New at Chemotechnique – Chemotechnique - Post-COVID
Hapten of the Quarter – Hydroperoxides of Limonene and Linalool
Hot Topic – EAACI Position Paper on Diagnostic Allergens
Literature Review 1 – Legislation on Medical Devices: What’s in it (and what’s not)?
Literature Review 2 – Quantification of Preservatives in Tattoo and Permanent Make-up Inks in the frame of the new Requirements under the REACH Regulation
Literature Review 3 – Update on Metal Implant Allergy
Literature Review 4 – Nickel and Cobalt Release from Beauty Tools: A Field Study in the German Cosmetics Trade
Advertorial – Chemo Nickel Test + Chemo Cobalt Test
Literature Review 5 – How to Test for Fragrance Allergy – Are the current Baseline Markers Useful?
Literature Review 6 – Limonene and Linalool hydroperoxides review: Pros and Cons for routine Patch Testing
Website Review - CAMP
Congresses & Exhibitions - update
Total number of Pages = 46
The Patch Tester #13
January 2023
Contents
What's New in Patch Testing – The European Baseline series and Recommended Additions 2023
Chemotechnique Staff Interview – Orders & Shipping Department
Hapten of the Quarter – Cobalt
Hot Topic – Patch Testing for Cutaneous Drug Reactions in Paediatrics - Review
Advertorial – Chemotechnique Spot Tests
Literature Review 1 – The Benefit of Late PT readings in Corticosteroid Allergy
Literature Review 2 – Patch Test results in Synthetic Garments in textile-dye positive Patients
Literature Review 3 – ACD caused by topical Ophthalmic Medications
Literature Review 4 – Evaluation of Lymphocyte Transformation Tests as compared with PT in Nickel allergy Diagnosis
Literature Review 5 – Utility of PT and Lymphocyte Transformation Tests for Metal Allergy with Orthopaedic Implants
Literature Review 6 – Contact Allergy to Cannabis and related Essential Oils
Literature Review 7 – Delayed-type reactions to Perennial Moulds in an Atopic Patient
Website Review - MELISA.org
Congresses & Exhibitions - Update
Total number of Pages = 42
The Patch Tester #14
March 2023
Contents
What's New in Patch Testing – New PT Chamber from Chemotechnique
What's New at Chemotechnique – New BasIQ Patch Test Chamber
Hapten of the Quarter – Sorbitan Sesquioleate
Hot Topic – Metalworker Allergy
Advertorial – Chemotechnique PT Chambers
Literature Review 1 – The use of Sorbitan sequioleate in patch test preparations and patch testing with the substance
Literature Review 2 – Nickel allergy is associated with broad-spectrum cytokine response
Literature Review 3 – Path Test results in a Dutch Paediatric Population with suspected ACD - A Retrospective Cohort Study
Literature Review 4 – The Additive Value of Patch Testing non-commercial test substances and patients own products in a clinic of Occupational Dermatology
Literature Review 5 – Presentations to Emergency Departments in Melbourne Australia diagnosed as ACD
Literature Review 6 – The Use of Carvone in consecutive Patch Testing
Website Review - Revised Patch Tester website
Congresses & Exhibitions - Update
Total number of Pages = 34.
The Patch Tester #15
June 2023
Contents
Editorial article - Haptens and Allergens
Inside Chemotechnique – BasIQ Ultra Chambers
Hapten of the Quarter – Lanolin
Literature Review 1 – Systematic Review of Allergic and Irritant Dermatitis of the Vulva
Literature Review 2 – Epoxy Allergy: Investigation of a modern industry
Literature Review 3 – Shedding a Light of the Importance of Photo-patch testing
Literature Review 4 – Contact Sensitisation to Benzoisothiazolinone: IVDK Data for 2002 to 2021
Literature Review 5 – Sunscreens: A Review of UV Filters and their allergic potential
Literature Review 6 – Contact Dermatitis in the Surgical Patient: A Focus on Wound Closure Materials
Website Review 1 - Chemotechnique UK distributor:
Canute Pharma
Website Review 2 - Chemotechnique Spain distributor: Sugelabor
Congresses & Exhibitions - Update
Total number of Pages = 44
The Patch Tester #16
September 2023
Contents
What's New in Patch Testing
The revised new Chemotechnique NACDG-80 Series
Advertorial
New BasIQ Chambers
Hapten of the Quarter
Hydroperoxides of Limonene and Linalool
Hot Topic
Patch Testing 5th edition, book by Anton C. de Groot
Literature Review 1
NACDG Patch Test results 2019-2020
Literature Review 2
Occupational Contact Allergy: The European Perspective - Analysis of Patch Test data from ESSCA 2011-2020
Literature Review 3
Contact Allergy to Gold, tested in two different Chambers
Literature Review 4
Patch Testing with Cobalt in Adults: An NACDG Experience 2001-2018
Literature Review 5
Emerging Allergens in Eyelash and Eyebrow Cosmetics
Literature Review 6
Chromium in Cement Samples from inside and outside the EU; A study from the ECDRG.
Website Review - ACDS
Congresses & Exhibitions - Update
Total number of Pages = 40
The Patch Tester #17
December 2023
Contents
What's New at Chemotechnique
New Patch Test Product & Reference Manual 2024
Advertorial
Chemo Nickel Test & Chemo Cobalt Test
Hapten of the Quarter
Sesquiterpene lactone mix
Hot Topic
Changes to the North American Series
Literature Review 1
Contact Allergy to Corticosteroids: is the European Baseline Series Sufficient?
Literature Review 2
Long-term prognosis of Vaccine Induced Contact Allergy to Aluminium: Third Patch Test with additional test preparations.
Literature Review 3
Fragrance Allergens in Cosmetic products marketed for Children in Denmark.
Literature Review 4
Allergic Contact Dermatitis from Essential Oils in Consumer Products.
Literature Review 5
Nickel Release from Hairdressing Tools in USA.
Literature Review 6
Potential for Allergic Contact Dermatitis in Popular Hair care products and practices.
Website Review
European Society for Contact Dermatitis.
Congresses & Exhibitions - Update
Total number of Pages = 38 pages.
The Patch Tester #18
March 2024
Contents
Editorial - The Future of Patch Testing in the EU
Hapten of the Year – Sulphites
Hot Topic – Why Allergists should Patch Test
Literature Review 1 – Results of Patch Testing to Botanicals
Literature Review 2 – Piloting Photographic Photonic Patch Testing
Literature Review 3 – Patterns of simultaneous contact allergies in patients with contact sensitisation to oxidised Linalool and oxidised Limonene
Literature Review 4 – The Contribution of Metal Allergy to the Failure of Metal Alloy Implants, with special reference to Titanium
Literature Review 5 – Contact Allergy in African Countries
Literature Review 6 – Frequency and Relevance of Contact Allergy in Dental Patients
Website Review 1 - EAACI
Congresses & Exhibitions - Update
Total number of Pages = 40
The Patch Tester #19
June 2024
Contents
What's New in Patch Testing? - Litigation in Contact Dermatitis
Hapten of the Quarter – 2-HEMA
Hot Topic – Doubtful Patch Test Reactions
Literature Review 1 – Clinical Relevance of Doubtful Patch Test Reactions
Literature Review 2 – 2-HEMA: A Global Epidemic at its peak in Spain
Literature Review 3 – Declining Frequency of Sensitisation to FM-I and FM-II - IVDK Data
Literature Review 4 – Analysis of Preservatives and Fragrances in topical Medical Devices - the need for more stringent regulation
Literature Review 5 – Results of Patch Testing with 5 new Fragrance Materials
Literature Review 6 – Association between Atopic Disease and Vaccination Granulomas
Literature Review 7 – Patch Test with Nickel, Cobalt and Chromium in Patients with Suspected Allergic Contact Dermatitis
Congress Review - EAACI
Congresses & Exhibitions - Update
Total number of Pages = 34
The Patch Tester #20
September 2024
Contents
Hot Topic – Will all EU member states risk the same severely compromised supply of Patch Test haptens as Germany?
Hapten of the Quarter – Lanolin - just how much of a Hapten is it really?
Literature Review 1 – The Significance of Dose for the Patch Test Reaction
Literature Review 2 – Chromium and Cobalt in Leather: A Danish market survey
Literature Review 3 – Titanium Allergy: A Retrospective Review of 166 Patch Tested Patients
Literature Review 4 – Less efficient skin penetration of the metal allergen Pd2+ compared to Nickel 2+ and Co2+from Patch Test preparations
Literature Review 5 – Occupational Allergic Contact Dermatitis to Marijuana
Literature Review 6 – Allergic Contact Dermatitis caused by Colophonium in Resin Creams
Literature Review 7 – Comparison of Patch Test positivity after 24 and 48 hours of occlusion time in Patents of Allergic Contact Dermatitis: A prospective study.
Literature Review 8 – Patch Test results amongst Older Adults: A retrospective analysis of the NACDG date (2009 – 2020)
Literature Review 9 – Patch Testing and Allergic Contact Dermatitis in Pregnancy
Literature Review 10 – A Re-assessment of the value of markers of Corticosteroid contact allergy in the Spanish Baseline Series: Clobetasol propionate in the spotlight
Congress/Website Review - ESCD Dresden 4th to 7th September 2024
Congresses & Exhibitions - Update
Total number of Pages = 48
The Patch Tester #21
June 2025
Contents
Hot Topic – Pre- and post-Implant Patch Testing
Hapten of the Quarter - Gold
Literature Review 1 – Patch Tests for non-immediate cutaneous drug reactions: Late readings on Day 4 is more sensitive than on Day 3
Literature Review 2 – Ear Dermatitis after wearing Earrings: Rhodium sensitivity
Literature Review 3 – Allergic Contat Dermatitis from Titanium secondary to surgical brow lift: A case report with a 4-year follow-up
Literature Review 4 – Results of Patch Testing Propolis in the European Baseline series: A 4-year retrospective study
Literature Review 5 – Allergic Contact Dermatitis in Adults, with and without Atopic Dermatitis: Evaluation of the Spanish Contact Dermatitis Registry (REIDAC)
Literature Review 6 – Concordance of different sources for Nickel Sulphate patch testing
Literature Review 7 – The Value of Patch Testing of Plants "as is" in diagnosing Plant sensitisation
Literature Review 8 – Photopatch Testing: Clinical characteristics, test results, and final diagnoses from the NACDG 20009-2020
Literature Review 9 – Characterisation of paediatric Patch Tesing: A retrospective review, 2020-2023.
Congress/Website Review - Skin Health Institute of Australia + Contact Allergen Bank of Australia
Congresses & Exhibitions - Update
Total number of Pages = 46
The Patch Tester #22
December 2025
Contents
Hot Topic – Glucose Sensors & Insulin Pumps
Hapten of the Quarter - ACDS Allergen of the Year Toluene-2,5-Diamine Sulphate
Literature Review 1 – Disease-reated Internet Use and its Relevance to the Patient-Physician Relationship in Atopic Dermatitis: A cross-sectional study in Germany
Literature Review 2 – Patch testing to Mentha piperita (Peppermint oil): The NACDG Experience (2009-2020)
Literature Review 3 – Contact Dermatitis secondary to Povidone iodine: A systematic review
Literature Review 4 – Incidence of Allergic Contact Dermatitis in Finland 1998 - 2021: A nationwide registry-based study
Literature Review 5 – Patch Test results to the Spanish Baseline test series according to age groups: A multicentric prospective study from 2019 to 2023
Literature Review 6 – Comparison of patch testing Brazilian (Green) Propolis and Chinese (Poplar type) Propolis: Clinical epidemioloical study using data from the Information Network of Departent of Dermatology (IVDK)
Literature Review 7 – Long-term observations on the European PhotoPatch Test Baseline Series (EPTBS) in real clinical practice: 11 years of results in a Spanish cohort and suggestions for an EPTBS update
Congress/Website Review - ACDS CAMP 2.0
Total number of Pages = 36.
The Patch Tester #23
February 2026
New Format...
Total number of Pages = ~12.